The Cell of humans contain large amount of DNA in their composition.If any changes occur by mistake or during replication is known as mutation in cell.If mutation occur in somatic cell is not pass to next generation but occur in genetic cell it transfer to offspring.
▉ Classification of mutation.
- Chromosomal mutation.
Chromosomal mutation occur in chromosome the number of chromosome change by addition of extra chromosomes or removal of chromosomes.This chromosomal change lead to syndrome of klinefelter,or down.
- Point mutation.
The alteration of DNA nucleotide sequence and affect the message of command center is known as point mutation.
Environmental factors also affect cell is called mutagen factors.
▉ There are following types of mutation.
- Sense mutation.
Some change in gene have no affect on function of gene is called sense mutation.
- Non sense mutation.
If mutation affect on function is called non sense mutation.
- Frame shift mutation.
If difficult to reading of sequences is called frame shift reading.
- Changes in gene position.
B gene or B protein may be regulated differently because of change in gene position.
- Chromosomal rearrangement.
B gene may be inactivated or regulation differently in its new location on chromosomes.